The Best Direct-Entry MSN Programs (No BSN Required) 2026

Genevieve Carlton, Ph.D.
By
Updated on January 6, 2026
Edited by
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RN-to-MSN programs allow registered nurses — including those with associate degrees — to pursue master’s degrees and nurse practitioner roles.

A master of science in nursing (MSN) degree can open new doors and increase your earning potential. And you don’t need to earn a separate bachelor of science in nursing (BSN) before starting an MSN degree.

If you have a bachelor’s degree in a subject other than nursing but would like to become a nurse, direct entry MSN bridge programs streamline your path to a graduate degree in nursing and help save you time and money in the process.

We’ve identified and ranked the nation’s top direct entry MSN programs to help you make the best decision for your nursing career.

The Best MSN Programs With No BSN Required of 2026

We use trusted sources like Peterson's Data and the National Center for Education Statistics to inform the data for these schools.
from our partners appear among these rankings and are indicated as such.

Emory University — Most Flexible for Students

  • Atlanta, GA
  • 4 year
  • Campus + Online
  • Accredited

Why We Chose EU: Online MSN Courses, High Level of Financial Aid, and Diverse Specialty Areas

Emory University's MN to MSN pathway requires 60 credits you can complete in four semesters.

You’ll spend the first 15 months preparing to pass the NCLEX-RN and become a registered nurse and earn a master of nursing degree. Then, through the InEmory Scholars Program, you can work as an RN or choose to continue your education to earn your MSN or DNP.

MSN graduates can become licensed and certified as a nurse practitioner in family, adult-gerontology primary care, pediatric primary care, or women’s health. 

Tuition costs $26,425 per semester. About 92% of students in the School of Nursing received $7.1 million in financial assistance. Emory is also a Yellow Ribbon school that offers a maximum of $7,500 per student for 20 students who qualify through the VA. 

Other Highlights: 

  • Accredited by the CCNE 
  • 555 clinical hours and 142.5 simulation hours
  • 30 service learning hours

Good to Know:

  • Requires a non-nursing bachelor’s degree, 3.0 or higher cumulative GPA preferred 
  • Seven prerequisites are required with a grade of C or better
  • $50 application fee 

35%

Online Enrollment

$46,800

Avg. Grad Tuition, In-State

96%

Retention Rate

$46,800

Avg. Grad Tuition, Out-of-State
Acceptance Rate
10%
Students Enrolled
15,179
Institution Type
Private

Northeastern University — Best Program for Prospective Nurse Practitioners

  • Boston, MA
  • 4 year
  • Campus + Online
  • Accredited

Why We Chose NU: Choose from Five NP Specializations after Gaining RN Licensure

We chose Northeastern University's direct-entry MSN because it offers aspiring nurse practitioners five NP specialty tracks to choose from: adult-gerontology acute care, family, neonatal, pediatric primary care, or psychiatric mental health. 

The first four semesters of the program prepare you to become a registered nurse with BSN coursework. Then, after you complete 1-2 years of nursing experience, you’ll return to the program part-time or full-time to earn your MSN in 36-42 credits and become an NP. 

Other Highlights: 

  • Accredited by CCNE
  • Yellow Ribbon school that pays the maximum funding for all eligible graduate students
  • Prepares students to sit for the NCLEX and the NP specialty exam of their choice 

Good to Know:

  • Must begin the program in the fall 
  • Tuition costs $23,298 per semester. 
  • Requires a non-nursing bachelor’s degree and a minimum GPA of 3.0 

27%

Online Enrollment

$27,728

Avg. Grad Tuition, In-State

97%

Retention Rate

$27,728

Avg. Grad Tuition, Out-of-State
Acceptance Rate
5%
Students Enrolled
39,774
Institution Type
Private

University of California-Irvine — Best On-Campus Experience

  • Irvine, CA
  • 4 year
  • Campus + Online
  • Accredited

Why We Chose UC Irvine: Mixed Learning Communities, Smaller Cohort Sizes, and High-Tech Simulation 

We chose UC Irvine's master's entry to nursing because the 84-credit full-time, on-campus direct-entry program offers interprofessional learning opportunities, high-tech clinical simulation experiences, clinical partnerships throughout UCI Health, and small cohort sizes. 

The two-year program offers classes in the spring and fall semesters. It prepares you to take the NCLEX-RN and become a registered nurse in many specialties, including public health or leadership roles. The program meets the requirements to become a certified public health nurse in California. You can also pursue advanced degrees in research, clinical specialization, nursing education, and/or administration. 

Program Highlights:

  • Hispanic-Serving Institution 
  • Only seven prerequisite courses with a letter grade of C or higher required
  • Concentration available in community and population health

Good to Know:

  • California residents pay $35,782 for tuition per year, and nonresidents pay $48,026 per year. 
  • Only one start date (fall)
  • The program is highly competitive; a non-nursing bachelor’s degree and a 3.0 GPA are required. 

37%

Online Enrollment

$12,264

Avg. Grad Tuition, In-State

94%

Retention Rate

$27,366

Avg. Grad Tuition, Out-of-State
Acceptance Rate
29%
Students Enrolled
37,296
Institution Type
Public

University of California-Los Angeles — Best for Students Interested in Public Health Nursing

  • Los Angeles, CA
  • 4 year
  • Campus + Online
  • Accredited

Why We Chose UCLA: Pursue a Public Health Nursing Certificate Along With RN Licensure

UCLA's master’s entry to clinical nursing is a two-year program that is ideal for aspiring RNs who wish to pursue public health nursing certification in California. The program prepares bedside nurses rather than APRNs. You need at least one year of nursing experience before you apply to an advanced practice program.

This full-time on-campus program requires 102 cumulative units, including clinical hours that you’ll complete at affiliated hospitals. The program costs $62,609 for California residents and $87,099 for nonresidents, plus an additional $13,600 for two years of health insurance coverage for both residents and nonresidents. 

Other Highlights: 

  • Graduates can pursue public health nursing certification through the California State Board of Nursing. 
  • No GRE required
  • Qualifying employees at UC may be eligible to receive a 66% reduction in tuition and student services fees for four courses or 12 units, whichever is greater. 

Good to Know:

  • Only one start time in the fall
  • Requires 11 prerequisite courses and three recommendation letters 
  • Can only apply AP credit with a score of 4 or higher to one prerequisite course

12%

Online Enrollment

$12,264

Avg. Grad Tuition, In-State

97%

Retention Rate

$27,366

Avg. Grad Tuition, Out-of-State
Acceptance Rate
9%
Students Enrolled
48,656
Institution Type
Public

Vanderbilt University — Quickest Path to Master's Degree

  • Nashville, TN
  • 4 year
  • Campus + Online
  • Accredited

Why We Chose VU: Earn Your MSN in Just Four Semesters

VU's MN program allows students to sit for the NCLEX-RN and become a master’s-prepared registered nurse in four semesters or 64 credits. The fully on-campus program offers two start dates in the fall and spring semesters, but you must live within daily commuting distance of the campus. 

You can pursue the MN prespecialty, a degree track that guarantees your spot and allows you to move directly into your preferred post-master’s certificate specialty program after completing your MN degree.

Other Highlights:

  • Accredited by the CCNE
  • Yellow Ribbon School that offers up to $16,000 for eligible graduate students
  • Every full-time nursing graduate student receives a scholarship unless their tuition is paid in full by another scholarship source.

Good to Know:

  • Tuition costs $2,057 per credit, plus $8,377 in annual fees, which includes health insurance if you get it through the university’s student health plan.
  • Must hold a non-nursing bachelor’s degree
  • Health insurance is required for all students, and you will be billed automatically for the university’s student health insurance plan if you do not provide proof of adequate coverage by another insurer.

10%

Online Enrollment

$54,744

Avg. Grad Tuition, In-State

96%

Retention Rate

$54,744

Avg. Grad Tuition, Out-of-State
Acceptance Rate
6%
Students Enrolled
13,575
Institution Type
Private

badge-check How We Choose Schools

At NurseJournal.org, we use a data-driven methodology to identify deserving nursing programs around the country, making it easy for you to find a program that meets your needs. Our lists are informed by data from the most reputable sources, including the U.S. Department of Education. Our vetting process also includes a quality assurance team that evaluates data for accuracy.

Each school in this list is awarded a superlative based on metrics that we believe matter most to nursing students, including academic quality, affordability, career outcomes, accessibility, inclusivity, and individual program offerings, among other factors. Since many programs share similar offerings, our goal is to simplify your decision-making by highlighting features that are most relevant to your needs. We reserve the right to exclude schools that lack sufficient data for accurate calculations.

All data was verified in November 2025.

Using Our Rankings: What To Look For in an MSN Program with No BSN

What should you look for when choosing an RN-to-MSN program? The following are major factors that should guide your search.

Admission Requirements

Check whether you meet the program’s education and clinical experience requirements.


Specializations

Nursing schools offer multiple MSN specializations, so make sure the programs on your list feature concentrations in your chosen areas.


Program Curriculum

Review the program’s course requirements to see what you’ll study and learn more about whether the program aligns with your professional interests.


Clinical Experience

Look at the clinical requirements and the format, including whether the school assists with clinical placements, to find a good fit.


Accreditation

Licensure requires an accredited nursing degree, so restrict your search to programs accredited by the Accreditation Commission for Education in Nursing or the Commission on Collegiate Nursing Education.


Program Length

RN-to-MSN programs typically require 24-36 months. However, APRN programs, including MSN degrees for nurse practitioners, may take more than 36 months.


School NCLEX Pass Rate

While RNs have already passed the NCLEX exam, checking a school’s pass rate can provide valuable information on how well it prepares graduates for nursing careers.

Why Is Program Accreditation Important?

Nursing school accreditation recognizes programs that meet national quality standards and follow industry best practices. Choosing an accredited RN-to-MSN program is crucial for your career and ensuring your eligibility for licensure. Credits from non-accredited curriculums rarely transfer to programs with accreditation.

Additionally, the government only offers federal grants and loans to students in accredited nursing schools and programs. So, enrolling in a direct entry MSN program with accreditation is the most economical and efficient course. Our guide lists only accredited programs.

Applying to Direct Entry MSN programs

Applying to a direct entry MSN program is a great first step in taking your career to the next level by earning a master’s degree. Admission requirements vary depending on the school, but most programs require the following:

  • Bachelor’s degrees in non-nursing field
  • GPA of 3.0 or higher
  • Academic transcripts
  • At least one year of clinical nursing experience
  • Criminal background check and fingerprinting
  • Personal essay
  • Letters of recommendation
  • TOEFL or IELTS (English proficiency tests for non-native English speakers)
  • Interview
  • GRE or MAT scores (requirement of some schools)

Prerequisite classes ensure prospective MSN students are adequately prepared for the rigor of a master’s degree. Here are the seven most common prerequisites:

  • Anatomy and physiology
  • Microbiology
  • Nutrition
  • Pathology
  • Pharmacology
  • Psychology
  • Statistics

Institutions commonly offer these classes through online learning, including lab requirements.

Paying for Your Program

Earning an MSN degree is an excellent investment in your future but can carry a large price tag, making it challenging to pay for your direct entry MSN program with savings or current earnings. Fortunately, plenty of organizations and institutions understand the importance of this issue and want to set you up for success.

Identifying available financial aid options, including grants and scholarships, can help lower your financial burden. After meeting eligibility requirements, you do not have to pay back these forms of aid. Be sure to check with your employer to see if they offer financial assistance programs, including tuition reimbursement or education funds.

Nursing student loans, on the other hand, must be paid back — often with interest. The federal government offers loans to graduate students attending accredited institutions.

You can also pursue loan forgiveness and consolidation programs as a nursing student, including offers that require you to work for a period in an underserved area. Some nurse-specific loan forgiveness options include:

When estimating costs beyond tuition, consider whether you must adjust your work schedule during clinicals or when studying for exams. Factor in other program expenses, such as textbooks and any additional equipment. You may also have expenses related to clinical placements, including tolls, gas, parking, and meals on clinical days.

RN-to-MSN Salary and Career Outlook

Compared to their peers with bachelor’s and associate degrees, nurses with MSNs can benefit from much higher earning potential. Payscale data from September 2025 show that, on average, master’s-level nurses earn almost $30,000 more annually than ADNs.

Average Nurse Salaries by Degree Level
Nursing DegreeAverage Annual Salary (October 2025)
MSN$109,000
BSN$99,000
ADN$80,000
Source: Payscale

Most MSN graduates become advanced practice registered nurses (APRN) to work as nurse practitioners (NP), clinical nurse specialists (CNS), and nurse-midwives. Still, there are other possibilities for direct entry MSN graduates, including nurse educator, nurse informaticist, and nurse administrator roles. Many nurse leadership positions require at least a master’s degree.

With the need for mental healthcare on the rise, psychiatric nurse practitioners may experience strong demand and lucrative salaries. You may also consider earning a doctor of nursing practice (DNP), which is the highest degree in nursing and a requirement for becoming a .

While a nurse anesthetist is the highest-paid nurse specialization, NPs also earn an average six-figure income.

As with other professions, nursing income varies according to specialty, geographic area, work setting, and other factors.

Average Nurse Salaries by Specialization
Nurse SpecialtyAverage Annual Salary (2025)
Nurse Anesthetist$192,885
Psychiatric Nurse Practitioner$125,736
Nurse-Midwife$111,891
Family Nurse Practitioner$108,317
Clinical Nurse Specialist$105,704
Nursing Manager$100,248
Nurse Educator$87,739
Payscale

Frequently Asked Questions

These programs typically require approximately two years. During this time, you’ll complete undergraduate and graduate nursing courses. If you’re enrolling part-time or specializing as a nurse practitioner, you’ll likely spend 3-4 years in a program.